Peptic Ulcer drug therapy

September 21, 2009 · Posted in Treatment of gastric ulcer 

Most Helicobacter pylori peptic ulcer can be clear or stop using non-steroidal anti-inflammatory drugs and to be cured and to prevent recurrence.

 Drug use is as follows:

 To reduce gastric acid secretion in gastric ulcer;

 If confirmed Helicobacter pylori infection by clearing the stomach wall of bacteria to treat ulcers;

 Through the protection of gastric mucosa or upper small intestine (duodenum) to control non-steroidal anti-inflammatory drugs to their damage.

 The choice of drugs

 To reduce gastric acid secretion of drugs

 To reduce gastric acid secretion in peptic ulcer drugs applicable to all.

 Proton pump inhibitors: such as omeprazole, lansoprazole slow-release agents, rabeprazole, Pan Dora zole and resistance to the letter, they can reduce gastric acid secretion (which was better than H2 receptor blockers) .

 H2 receptor blockers: such as cimetidine, Sandostatin stomach (ranitidine), famotidine, and love the Greek (nizatidine), they can reduce gastric acid secretion.

 Antacids: China and the gastric acid, but its effect than the H2 blockers and proton pump some difference.

 If it is caused by the Helicobacter pylori peptic ulcer, but the use of proton pump inhibitor combined with antibiotic therapy.

 Helicobacter pylori antibiotic

 Doctors issued a joint drug program can treat Helicobacter pylori, drug combination therapy including at least two kinds of antibiotics, a proton pump inhibitor in some cases can also be a co-bismuth compound.

 Prevention of ulcer drugs

 Some drugs are used to protect the long-term application because of non-steroidal anti-inflammatory drugs or aspirin-induced stomach damage. These drugs known as prostaglandin analogs, such as colloidal bismuth subcitrate, they can prevent non-steroidal anti-inflammatory drug-induced ulcers.

 Issues to be considered

 Stomach ulcer (gastric ulcer) healing time than the upper small intestine (duodenum) ulcers longer.

 For since the Helicobacter pylori-induced peptic ulcer, the doctor recommended combination therapy including at least two kinds of antibiotics and an antacid (usually proton pump inhibitors) sometimes also require the co-bismuth compounds. The combined medication cure rate of 80% -90% around and can significantly reduce the chance of recurrence.

 Routine can spare some H2 blockers and proton pump inhibitors, these non-prescription. If the application-the-counter antacid category, such as omeprazole or famotidine 10-14 days can help treat these symptoms, if symptoms are severe, it would need to see a doctor promptly.

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