So what’s pathological features of chronic gastritis
1, superficial gastritis, gastric inflammation limited to the concave surface and the lamina propria. The naked eye see the mucosal hyperemia, edema, or accompanied by exudation, mainly seen in the antrum, but also found in the gastric body, and sometimes see a small amount of erosion and bleeding. Microscope, there are shallow membrane of neutrophils, lymphocytes and plasma cell infiltration, deep glands intact. In addition, some patients have more gastric antrum erosion lesions, or associated with a higher number of warts off raised, saying that chronic erosive or verrucous gastritis.
2, atrophic gastritis, inflammation of mucous membranes in depth when the impact of the lamina propria of gastric glands to make it shrink, called atrophic gastritis. Gastric mucosal layer thinning, disappearance of mucosal folds flat or can be diffuse, but also showed limitations. Microscope, part of the disappearance of gastric glands, the individual may completely disappear, mucous layer, submucosa with lymphocytes and plasma cells infiltration. Sometimes, mucosal atrophy may be complicated by gastric pit epithelial cell proliferation, leading to local mucosal layer thickening instead, saying that the formation of atrophic gastritis with too. Such as the spread of inflammation extensive destruction of a large number of glands, so that the whole gastric body mucosa atrophy thinning, called gastric atrophy.
Atrophic gastritis can occur intestinal gland metaplasia and pseudo-pyloric gland metaplasia, in the proliferation of the gastric pits and intestinal metaplasia can occur on the basis of epithelial dysplasia (dysplasia). Dysplasia is a non-normal mucosa, with atypical cells, poorly differentiated and mucous membranes characterized by structural disorder that is most likely precancerous lesions.
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