Treatment of gastric ulcer drug, “group discussions”
Acid suppression and protection of the mucosa to be broken down
Gastric ulcer patients with gastric acid secretion may be normal or low, is the main mechanism of defense, repair weakened, at this time of acid suppression therapy is not the most important measures, especially for those who actually harmful to the lower gastric acid secretion. At this point should be to protect the gastric mucosa as the main measures, such as taking sucralfate, bismuth potassium citrate, misoprostol and so on. With proper diet treatment, tobacco and alcohol Eat less spicy.
Most of duodenal ulcer patients with gastric acid secretion is increased, the disease pathogenesis is the invasion of the main factors that enhanced acid-suppressing drugs therefore indispensable; but to protect the gastric mucosa as a major role in this effect is greatly reduced drug , such as taking Sucralfate for the treatment of duodenal ulcer almost no effect.
Make good use of drugs and antispasmodic drugs power
Ulcers in patients with vagus nerve normal or low, resulting in slower gastric motility, peristaltic weakened, this time application of multi-Pan ketone, metoclopramide to increase gastric motility, food, stomach acid and various digestive enzymes from the stomach and timely sent, in order to minimize the erosion of gastric mucosa.
Duodenal ulcer in patients with vagus nerve was stimulated state, gastric acid secretion increased, this time applied to promote gastrointestinal motility drugs, not only useless in the disease, but to make large quantities of food rapidly into the duodenum, stimulate the secretion of gastric duodenal a large number of hormone secretion, resulting in a significant increase in stomach acid, so they had a simple duodenal ulcer complicated by gastric ulcer, has become complex ulcer, but also increase the difficulty of treatment.
How to treat two kinds of ulcers
When a patient diagnosed as peptic ulcer, do not rush to triple or quadruple therapy applied indiscriminately, but should be further refined as a gastric ulcer or duodenal ulcer. For the acid number should be proton-pump inhibitor-based triple therapy, we should fully take into account the spirit of the factors on the promotion of the role of gastric acid secretion may be an appropriate compatibility sedative drugs, such as stability, more equality into account.
The main mechanism for duodenal ulcer disease is the invasion of factors increases, so in order to improve efficacy, shorten treatment, anti-cholinergic drug use are essential, such as belladonna, anisodamine so. Despite some side effects, drug side effects that disappeared after the closure will not result in large or irreversible physical damage.
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